Abstract background and aims: nonalcoholic fatty liver disease (nafld) is common in severely obese subjects and can progress to cirrhosis and liver failure. viagra first time dosage Predicting advanced or progressive disease may help in selecting patients for liver biopsy and assist the development of therapeutic options. Methods: liver biopsies were taken at laparoscopic obesity surgery in 105 consecutive patients. The clinical and biochemical variables were analyzed for correlation with specific histologic features. Results: twenty-six patients (25%) were found to have nonalcoholic steatohepatitis (nash), and 11 (42%) of these had advanced fibrosis. A raised index of insulin resistance (odds ratio [or] 9. viagra without prescription 3, 95% confidence interval [ci] 3. 4-26), systemic hypertension (or 5. 2, 95% ci 2. 0-13. 5), and raised alanine aminotransferase (or 8. 6, 95% ci 3. buy viagra cheap 1-23. cheap viagra pills 5) were independent predictors of nash. A combination of 2 or 3 of these predictors allows a sensitivity of 0. order viagra online 8 and specificity of 0. 89 for nash. viagra for sale Alcohol consumption was associated with a reduction in nash (or 0. pharmacy price for viagra 35, 95% ci 0. 12-1. viagra women dose dot 00) and diabetes (or 0. 18, 95% ci 0. 047-0. 67). Conclusion: insulin resistance and systemic hypertension, features of the metabolic syndrome, are independently associated with advanced forms of nafld. buy viagra Moderate alcohol consumption seems to reduce the risk of nafld in the severely obese, possibly by reducing insulin resistance. Comment in a wider view on diagnostic criteria of nonalcoholic steatohepatitis. viagra safe alcohol [gastroenterology. 2002] a wider view on diagnostic criteria of nonalcoholic steatohepatitis. Garcã­a-monzã³n c, fernã¡ndez-bermejo m. Gastroenterology. 2002 mar; 122(3):840-2. Pmid: 11438497 [pubmed - indexed for medline] mesh terms, substances mesh terms adult body mass index cholesterol/blood fatty liver/etiology* fatty liver/pathology* fatty liver/surgery female humans hypertension/complications insulin resistance laparoscopy liver cirrhosis/etiology male obesity, morbid/complications* predictive value of tests prospective studies risk factors substances cholesterol linkout - more resources full text sources elsevier science ebsco ohiolink electronic journal center other literature sources cos scholar universe labome researcher resource - exactantigen/labome medical clinicaltrials. Gov molecular biology databases cholesterol - hsdb miscellaneous swets information services supplemental content save items add to favorites loading related citations in pubmed predictors of nonalcoholic steatohepatitis and advanced fibrosis in morbidly obese patients. viagra safe alcohol [obes surg. 2005] predictors of nonalcoholic steatohepatitis and advanced fibrosis in morbidly obese patients. Ong jp, elariny h, collantes r, younoszai a, ch.

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